New Gene Therapy Targets Alzheimer’s

15 Feb

bankiewiczA new approach to delivering gene therapy to the brain to treat neurodegenerative diseases such as Alzheimer’s, was revealed in research findings published in the February 4 online edition of the Proceedings of the National Academy of Sciences.

UCSF neuroscientist Dr. Krystof Bankiewicz has developed a promising way to get nerve cells to help disperse gene therapy to targeted brain cells. He uses a technique called convection-enhanced delivery. The fluid containing the gene therapy is injected under pressure, delivered in pulses. Says Bankiewicz:

For the first time, specific regions of the cortex can be supplied with therapeutic agents by targeting defined regions of the thalamus…Translational experiments now are in progress to evaluate the potential of this unique gene delivery technology for the treatment of cortical dementias such as Alzheimer’s disease…

Bankiewicz’s research at UCSF has a strong focus on the development of practical approaches to gene and cell replacement therapies; he synthesizes several individual technologies into powerful new approaches to the treatment of such serious disease as brain cancer and neurodegenerative disorders, including Parkinson’s disease.

Source: Science Cafe

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